RESUMO
Objective:To analyze the medication law of Traditional Chinese Medicine (TCM) fumigation and washing to promote postoperative healing of hemorrhoids by data mining technology.Methods:The clinical literature about TCM fumigation and washing to promote postoperative healing of hemorrhoids was retrieved from the databases of CNKI, Wanfang, VIP, PubMed from the establishment of the databases to March 10, 2022. The frequency efficacy attributes, core medicinal pairs and core prescriptions of TCM were analyzed by using the Ancient and Modern Medical Records Cloud Platform (V2.3.5).Results:A total of 299 articles were included, involving 200 kinds of Chinese materia medica. The drugs used at high frequency ≥40 were Sophorae Flavescentis Radix, Phellodendri Chinensis Cortex, Natrii Sulfas, Galla Chinensis and Rhei Radix et Rhizoma and so on. The main efficacy was to clear heat and reduce dampness; cold, warm and slightly cold were the main medicinal properties, and the tastes were mainly bitter, pungent, sweet and sour, and most of the drugs return to the liver meridian, stomach meridian, heart meridian, large intestine meridian and so on. A total of 22 rules were obtained by correlation analysis. Five groups of drugs were obtained by clustering analysis. The core prescription drugs obtained by complex network analysis included Sophorae Flavescentis Radix, Phellodendri Chinensis Cortex, Natrii Sulfas, Galla Chinensis, Rhei Radix et Rhizoma, Taraxaci Herba, Borneolum Syntheticum, Sanguisorbae Radix, Atractylodis Rhizoma, Carthami Flos, Scutellariae Radix, Olibanum, Myrrha, and Lonicerae Japonicae Flos. Conclusion:TCM fumigation and washing can promote the postoperative healing of hemorrhoids mainly by clearing heat and reducing dampness and detoxification, as well as promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, restraining sore and generating muscle.
RESUMO
AIM: To study the protective effect of Yifusheng Capsule (YFSHC Radix Astragali, Radix Salviae Miltiorrhizae, Rhizoma Coptidis; Radix et Rhizma Rhei, etc.) on the islet ?-cells damages and renal lesions induced by streptozotocin (STZ) in diabetic rats. METHODS: The effect of YFSHC was observed on fasting blood glucose and insulin in induced diabetic rats, and the effect on ultramicro-structure of ?-cells and renal.( RESULTS:) Fasting blood glucose was decreased while serum insulin was increased. Islet ?-cells damages and renal lesions in induced diabetic rats were lessened significantly. CONCLUSION: YFSHC exerted a good protective and repairative effect on islet ?-cells damages as well as renal lesions.